中文名稱: ZFP36 抗原(重組蛋白)
英文名稱: ZFP36 Antigen (Recombinant Protein)
別 名: ZFP36 ring finger protein; TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
相關類別: 抗原
儲 存: 冷凍(-20℃)
概 述
Fusion protein corresponding to a region derived from 127-326 amino acids of human ZFP36
技術規(guī)格
Full name:
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ZFP36 ring finger protein
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Synonyms:
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TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A
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Swissprot:
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P26651
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Gene Accession:
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BC009693
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).
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