中文名稱: BNIP3抗原(重組蛋白)
英文名稱: BNIP3 Antigen (Recombinant Protein)
別 名: NIP3
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to N terminal 164 amino acids of human BNIP3
技術(shù)規(guī)格
Full name:
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BCL2/adenovirus E1B 19kDa interacting protein 3
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Synonyms:
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NIP3
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Swissprot:
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Q12983
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Gene Accession:
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BC021989
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Purity:
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>85%, as determined by Coomassie blue stained SDS-PAGE
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Expression system:
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Escherichia coli
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Tags:
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His tag C-Terminus, GST tag N-Terminus
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Background:
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This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2.
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