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  • 產(chǎn)品名稱：KCNJ11抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
KCNJ11抗原（重組蛋白）大部分抗體的運輸條件是一般的運輸過程需要1-2周的時間，所以是在4℃的條件下來完成的，4℃運輸*主要的目的是為了避免反復(fù)凍融對抗體活性的損害（如果使用干冰運輸，那么收到時抗體是凍起來的，為了分裝就需要解凍，這就多了一次凍融的過程），所以運輸過程中優(yōu)良避免干冰運輸！
詳情介紹：
中文名稱： KCNJ11抗原（重組蛋白）

英文名稱： KCNJ11 Antigen (Recombinant Protein)

別     名：  BIR; HHF2; PHHI; IKATP; TNDM3; KIR6.2

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 167-390 amino acids of human KCNJ11

技術(shù)規(guī)格

Full name:

potassium inwardly-rectifying channel, subfamily J, member 11

Synonyms:

BIR; HHF2; PHHI; IKATP; TNDM3; KIR6.2

Swissprot:

Q14654

Gene Accession:

BC112358

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.





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