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  • 產(chǎn)品名稱(chēng)：TSG101 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫(kù)存：35
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詳情介紹：

中文名稱(chēng)： TSG101 抗原（重組蛋白）

英文名稱(chēng)： TSG101 Antigen (Recombinant Protein)

別     名：  tumor susceptibility 101; TSG10; VPS23

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述：
 
Fusion protein corresponding to a region derived from 2-145 amino acids of human TSG101
   
技術(shù)規(guī)格

Full name:

tumor susceptibility 101

Synonyms:

TSG10; VPS23

Swissprot:

Q99816

Gene Accession:

BC002487

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.





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