中文名稱: 兔抗TCF7多克隆抗體
英文名稱: Anti-TCF7 rabbit polyclonal antibody
別 名: transcription factor 7; TCF-1
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: TCF7
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background:
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This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
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Applications:
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ELISA, IHC
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Name of antibody:
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TCF7
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Immunogen:
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Synthetic peptide of human TCF7
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Full name:
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transcription factor 7
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Synonyms:
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TCF-1
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SwissProt:
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P36402
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ELISA Recommended dilution:
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5000-10000
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IHC positive control:
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Human lung cancer and Human prostate cancer
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IHC Recommend dilution:
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40-200
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