別 名: TIMP metallopeptidase inhibitor 3; SFD; K222; K222TA2; HSMRK222
Full name: |
TIMP metallopeptidase inhibitor 3 |
Synonyms: |
SFD; K222; K222TA2; HSMRK222 |
Swissprot: |
P35625 |
Gene Accession: |
BC014277 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. |
