中文名稱: ACOT2抗原(重組蛋白)
英文名稱: ACOT2 Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Fusion protein corresponding to a region derived from 169-468 amino acids of human ACOT2
技術(shù)規(guī)格
Full name:
|
Acyl-CoA thioesterase 2
|
Synonyms:
|
MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128
|
Swissprot:
|
P49753
|
Gene Accession:
|
BC004436
|
Purity:
|
>85%, as determined by Coomassie blue stained SDS-PAGE
|
Expression system:
|
Escherichia coli
|
Tags:
|
His tag C-Terminus, GST tag N-Terminus
|
Background:
|
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. Acyl-CoA thioesterases, such as ACOT2, are a group of enzymes that hydrolyze Coenzyme A (CoA) esters, such as acyl-CoAs, bile CoAs, and CoA esters of prostaglandins, to the corresponding free acid and CoA. ACOT2 shows high acyl-CoA thioesterase activity on medium- and long-chain acyl-CoAs, with an optimal pH of 8.5. It is most active on myristoyl-CoA but also shows high activity on palmitoyl-CoA, stearoyl-CoA, and arachidoyl-CoA.
|